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CyFlow™ CD1b Purified

CyFlow™ CD1b Purified
Antigen: CD1b
Alternative Name: CD1, R1
Clone: SN13
Application: Flow cytometry, Immunohistochemistry, Immunoprecipitation
Format/Fluorochrome: Purified
Target Species: Human
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Isotype: IgG1
Order number: CG223656

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 1 mg/ml Quantity 0.1 mg Volume 0.1 ml Immunogen A cell membrane... more
CyFlow™ CD1b Purified
Concentration1 mg/ml
Quantity0.1 mg
Volume0.1 ml
ImmunogenA cell membrane antigen preparation that was isolated from normal human thymocytes
SpecifityThe mouse monoclonal antibody SN13 (K5-1B8) recognizes CD1b antigen, a 44 kDa type I glycoprotein associated with β2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells.
Background InformationCD1b (R1) together with CD1a and CD1c, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. Besides non-peptide glycolipid antigen presentation to CD1-restricted T cells, CD1b has been implicated in thymocyte development.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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