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CyFlow™ CD2 Purified

CyFlow™ CD2 Purified
Aplicación: Citometría de Flujo, Immunoprecipitation
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Isotype: IgG2b
Source Species: Mouse
Campo de aplicación: Immunophenotyping
Format/Fluorochrome: Purified
Antigen: CD2
Alternative Name: LFA-2
Clone: LT2
Número de pedido AH698236
HLDA Workshop HLDA VI—WS Code T 6T-008 Concentration Unit mg/mL Concentration 1... more
Información del producto "CyFlow™ CD2 Purified"
HLDA WorkshopHLDA VI—WS Code T 6T-008
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenNormal human blood lymphocytes
Background InformationCD2 (LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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