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CyFlow™ CD3 APC

CyFlow™ CD3 APC
Aplicación: Citometría de Flujo
Clonality: monoclonal
Regulatory Status: RUO
Campo de aplicación: Immunophenotyping, MHC
Format/Fluorochrome: APC
Láser: Red
Excitation Maximum: 650 nm
Pico de Emisión: 660 nm
Antigen: CD3
Alternative Name: Leu4, T3
Clone: 145-2C11
Target Species: Mouse
Isotype: IgG
Source Species: Hamster
Número de pedido BK375425

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

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Concentration Unit mg/mL Concentration 0,5 Quantity 0.1 mg Volume 0.2 mL... more
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Información del producto "CyFlow™ CD3 APC"
Concentration Unitmg/mL
Concentration0,5
Quantity0.1 mg
Volume0.2 mL
ImmunogenMouse BM10-37 cytotoxic T lymphocytes
Background InformationCD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3γ, CD3 δ, CD3ε and CD3ζ. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
UsageThe reagent is designed for Flow Cytometry analysis. Suggested working usage is 2·µg/ml. Indicated dilution is recommended starting point for use of this product, but working concentrations should be validated by the investigator.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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Technical Data Sheet

Instruction for Use

ECDoC

Certificate Of Analysis

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